Yu Li , Shaoqing Wang , Xingjiang Li

Author    Correspondence author
Cancer Genetics and Epigenetics, 2024, Vol. 12, No.   
Received: 01 Jan., 1970    Accepted: 01 Jan., 1970    Published: 11 Oct., 2024

Colorectal cancer (CRC), also known as colon cancer, is a leading cause of cancer-related deaths worldwide. Early detection of CRC is crucial as it significantly improves the chances of successful treatment and survival. Traditional diagnostic methods, such as colonoscopy, although effective, are invasive, costly, and often uncomfortable for patients. Therefore, there is a growing need for non-invasive diagnostic methods that are both sensitive and specific. These methods include measuring biomarkers in easily accessible body fluids like blood, stool, and urine. These biomarkers, such as DNA, RNA (including microRNAs), protei ns, and metabolites, can be detected through simple tests and have shown potential in CRC screening, early diagnosis, prognosis, and monitoring. Non-invasive biomarkers improve patient compliance, reduce costs, and enable personalized medicine. Additionally, they provide insights into the specific molecular characteristics of a tumor, allowing for tailored therapeutic strategies.