Soumeya N Fedala , Mahdi A Haddam , Farida Chentli , Akila Zenati , Radhia Si Youcef , Fatima Saraoui

1 bab el oued hospital, department of endocrinology, Algeria;
2 bab el oued hospital, department of biochemestry and genetics, Algeria;
3 ain naadja hospital, department of biochemestry, Algeria
Author    Correspondence author
International Journal of Clinical Case Reports, 2013, Vol. 3, No. 11   doi: 10.5376/ijccr.2013.03.0011
Received: 15 Aug., 2013    Accepted: 30 Aug., 2013    Published: 30 Aug., 2013

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The hypopituitarism of children, partial or absolute, stems from many causes. Tumor cause, such as craniopharyngioma, is predominant and must always be sought. The presence of a "tumor" pituitary lesion in a child with a GH deficiency, especially in family forms, should not overlook the possibility of a concomitant genetic disorder, in particular mutation of Prop 1. Surgical abstention in this case, with morphological and ophthalmologic monitoring are shown because the spontaneous regression of the hyperplasia pseudo tumor . We report two cases in this clinical regard. Keywords: pituitary insufficiency, GH deficiency, pituitary hyperplasia, Mutation of Prop. 1.

Pituitary insufficiency; GH deficiency; Pituitary hyperplasia; Mutation of Prop. 1.