Etiologies of Central Diabetes Insipidus in Children

Said Azzoug; Mourad Kesraoui; Farida Chentli

Etiologies of Central Diabetes Insipidus in Children

Said Azzoug

, Mourad Kesraoui

, Farida Chentli

Endocrinological Department Bab El Oued Hospital, Algiers, Algeria

Author

Correspondence author
International Journal of Clinical Case Reports, 2015, Vol. 5, No. 17 doi: 10.5376/ijccr.2015.05.0017
Received: 07 Feb., 2015 Accepted: 27 Mar., 2015 Published: 23 Apr., 2015

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Preferred citation for this article:

Azzoug et al., 2015, Etiologies of Central Diabetes Insipidus in Children, International Journal of Clinical Case Reports, Vol.5, No.17 1-2 (doi: 10.5376/ijccr.2015.05.0017)

Abstract

Background Central diabetes insipidus is a heterogeneous disease mainly due to lesions of hypothalamic nuclei or pituitary stalk caused by tumors of the suprasellar region or infiltrative diseases such as Langerhans cells histiocytosis or sarcoidosis.

Objective: The aim of our study was to analyze the etiologies of central diabetes insipidus in children.

Methods: Medical records of 31 children (mean age of 7 years) were reviewed.

Results Craniopharyngioma was the main etiology found in 71%, in 3.2% diabetes insipidus was secondary to autoimmune hypophysitis, in 3.2% it appears after radiotherapy for a germinoma of the pineal region, finally, in 22.6% it was considered as idiopathic.

Keywords

Diabetes insipidus; Craniopharyngioma; Hypophysitis; Germinoma

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