Said Azzoug , Farida Chentli

Endocrine diseases department Bab El Oued Hospital Algiers, Algeria
Author    Correspondence author
International Journal of Clinical Case Reports, 2015, Vol. 5, No. 36   doi: 10.5376/ijccr.2015.05.0036
Received: 05 Jul., 2015    Accepted: 06 Aug., 2015    Published: 08 Sep., 2015

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Azzoug S. and Chentli F., 2015, Juvenile Hyperthyroidism, International Journal of Clinical Case Reports, 5(36) 1-2 (doi: 10.5376/ijccr.2015.05.0036)

Background: Hyperthyroidism is less frequent in children than adults and its clinical profile is different.
Objective: The objective of our study was to analyze the clinical characteristics of hyperthyroidism in children and adolescents.

Subjects and Methods: It is a retrospective study concerning 161 patients (129 Females/32 Males) with mean age of 15.63 ± 3.51 years. Their medical records were reviewed.

Results: 98.1% have Graves’ disease. Appealing symptoms were thyrotoxicosis signs in 69%, ophtalmological signs in 15% and goiter in 16%. Diagnosis delay was of 20.73±20.69 months. Clinical presentation was obvious in 81% and discrete in 19%. Goiter was of type II/type III in 74% and of type I in 26%, exophtalmous was present in 69% and it was severe in 12.5%. Several complications were recorded, cardiothyreosis in 1.86%, dysglycemia in 13.04%, myopathy in 3.72% and behavioral disorders in 6.83%.

Conclusion: Graves’ disease is the main etiology of hyperthyroidism in children and adolescents; diagnosis is often delayed although it is clinically obvious so complications may occur. Therefore hyperthyroidism should be diagnosed and treated promptly.

Juvenile hyperthyroidism; Graves’ disease; Thyrotoxicosis; Goiter