Author Correspondence author
International Journal of Clinical Case Reports, 2024, Vol. 14, No. 1 doi: 10.5376/ijccr.2024.14.0005
Received: 13 Feb., 2024 Accepted: 21 Mar., 2024 Published: 02 Apr., 2024
Yang L.B., 2024, Genome driven personalized drug therapy, International Journal of Clinical Case Reports, 14(1): 40-47 (doi: 10.5376/ijccr.2024.14.0005)
Genome driven personalized drug therapy is an important medical field, which can achieve precise medication and prediction of drug side effects by analyzing patient genomic information. This method utilizes the association between gene mutations and drug reactions to predict patients' responsiveness to specific drugs and the risk of side effects. Genome driven personalized drug therapy can also predict drug targets and mechanisms of action, providing guidance for personalized treatment plans. However, this field still faces challenges, including difficulties in analyzing and interpreting genomic data, the complexity of individual genomic variations, and the interactions between genes and the environment. This review explores genome-driven personalized drug therapy from the perspectives of genome analysis and screening, personalized drug therapy strategies, and application fields, in order to continuously develop and bring more hope and potential for disease treatment.
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