Pankaj K. Gadhia , Salil N. Vaniawala

Molecular Cytogenetic Unit, S. N. Gene Lab. and Research Centre, President Plaza-A, Near RTO circle, Surat, India
Author    Correspondence author
International Journal of Molecular Medical Science, 2014, Vol. 4, No. 4   doi: 10.5376/ijmms.2014.04.0004
Received: 31 Oct., 2014    Accepted: 18 Nov., 2014    Published: 23 Dec., 2014

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Gadhia and Vaniawala, 2014, A Rare Double Aneuploidy with 48,XXY, +21 Karyotype in Down Syndrome from Gujarat, India, International Journal of Molecular Medical Science, Vol.4, No.4, 1-3 (doi: 10.5376/ijmms.2014.04.0004)
 

The occurrence of double aneuploidy in single individual is relatively rare phenomenon. A 12 – month old child has an extra X chromosome in addition to trisomy 21. The phenotypic characteristics of child were similar to Down syndrome. Cytogenetic finding revealed 48,XXY, +21 karyotype. Results have been discussed in light of published case reports on double aneuploidies of XXY, +21.

Double aneuploidy; Down syndrome; Klinfelter syndrome; Gujarat; India