Wei Wang

Cuixi Academy of Biotechnology, Zhuji, 311800, China
Author    Correspondence author
International Journal of Molecular Medical Science, 2023, Vol. 13, No. 2   doi: 10.5376//ijmms.2023.13.0002
Received: 07 Sep., 2023    Accepted: 15 Sep., 2023    Published: 22 Sep., 2023

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Wang W., 2023, Theoretical and historical development of gene editing and gene therapy, International Journal of Molecular Medical Science, 13(2): 1-7 (doi: 10.5376/ijmms.2023.13.0002)

Gene editing and gene therapy have been the forefront technologies in life sciences that have received increasing attention in recent years. They provide new avenues and methods for the treatment of human diseases and biological research. This review systematically elucidates the concepts and historical developments of gene editing and gene therapy. It introduces the definition, classification, technical principles, and application areas of gene editing, and reviews the origin, development, and commercialization of gene editing technologies. The definition, classification, technical principles, and application areas of gene therapy are analyzed, and the origin, development, and clinical application status of gene therapy technologies are discussed. Furthermore, the significance, prospects, challenges, and future directions of gene editing and gene therapy are explored. This review provides references and insights for a comprehensive understanding of gene editing and gene therapy, and scientific basis for advancing the application and development of gene editing and gene therapy in the field of biomedical research.

Gene editing; Gene therapy; Technological origins; Fundamental concepts; Historical development