Review and Progress

A Brief Analysis of the Principles and Application Prospects of Different Gene Editing Technologies  

Wei Wang
Institute of Life Science, Jiyang College of Zhejiang A&F University, Zhuji, 311800
Author    Correspondence author
International Journal of Molecular Medical Science, 2023, Vol. 13, No. 3   doi: 10.5376/ijmms.2023.13.0003
Received: 07 Sep., 2023    Accepted: 25 Sep., 2022    Published: 18 Oct., 2023
© 2023 BioPublisher Publishing Platform
This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Wang W., 2023, A brief analysis of the principles and application prospects of different gene editing technologies, International Journal of Molecular Medical Science, 13(3): 1-8 (doi: 10.5376/ijmms.2023.13.0003)



Gene editing technology is a precise modification technique targeted at DNA sequences, which has been widely applied in biomedical research, agriculture, and animal husbandry, among other fields. Gene editing technologies mainly include nucleases-based techniques, CRISPR-Cas system-based techniques, transcription activator-based techniques, and chemical modification-based techniques. Although these techniques employ different tools and methods for DNA sequence modification, their principles involve targeted cleavage of DNA sequences to induce double-strand breaks, followed by repair through intrinsic DNA repair mechanisms to achieve modification of the target genes. This review introduces the principles and applications of different types of gene editing technologies, analyzes their advantages and challenges, and discusses the future prospects of gene editing technology, providing valuable references and guidance for its research and applications.

Gene editing technology; CRISPR-Cas9; DNA repair; Application prospects
[Full-Text PDF] [Full-Text HTML]
International Journal of Molecular Medical Science
• Volume 13
View Options
. PDF(0KB)
Associated material
. Readers' comments
Other articles by authors
. Wei Wang
Related articles
. Gene editing technology
. DNA repair
. Application prospects
. Email to a friend
. Post a comment