Fang Jiang

Zhuji Central Hospital, Zhuji, 311800, China
Author    Correspondence author
Journal of Vaccine Research, 2024, Vol. 14, No. 1   doi: 10.5376/jvr.2024.14.0005
Received: 13 Feb., 2023    Accepted: 30 Mar., 2024    Published: 10 Apr., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Jiang F., 2024, Investigation on the differentiation and functions of immunological memory cells, Journal of Vaccine Research, 14(1): 31-38 (doi: 10.5376/jvr.2024.14.0005)

In the immune system, the synergistic action of innate and acquired immunity forms a robust defense mechanism. Innate immunity rapidly responds to invading threats through natural immune barriers and inflammatory reactions, while acquired immunity constitutes a relatively slower yet more specific and adaptive defense mechanism. The differentiation and functional regulation of immune memory cells represent a complex process. Following infection or immunization, a portion of immune cells transforms into memory cells, residing in the body's lymphoid tissues. These cells not only persist long-term but also, upon reencountering the same pathogen, can initiate immune responses more rapidly and effectively. This review will comprehensively and deeply study the differentiation and function of immune memory cells from the types, functions, and regulatory mechanisms, in order to provide new theoretical perspectives and foundations for future immunological research and therapies, thereby contributing to innovative immunotherapeutic approaches for humanity.

Immunological system; Immunological memory cells; Antigen; Differentiation; Regulatory Mechanisms