Review and Progress

Malaria Control: Advances in Vector Management and Vaccine Development  

Dawei  Wang
Hainan Provincial Center for Disease Control and Prevention, Haikou, 570206, Hainan, China
Author    Correspondence author
Journal of Vaccine Research, 2024, Vol. 14, No. 2   
Received: 01 Apr., 2024    Accepted: 03 May, 2024    Published: 15 May, 2024
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract

Malaria remains a significant global health challenge, necessitating continuous advancements in both vector management and vaccine development. This study synthesizes recent progress in these two critical areas. In vector management, traditional methods such as indoor residual spraying and insecticide-treated nets have faced challenges due to insecticide resistance, prompting the exploration of novel strategies including genetic manipulation, biological control agents, and evolution-proof insecticides. Concurrently, vaccine development has seen promising advancements with the RTS,S vaccine showing partial efficacy in Phase III trials and the emergence of next-generation vaccines targeting various stages of the Plasmodium life cycle. The integration of these innovative approaches in vector control and vaccine development holds potential for more effective malaria control and eventual eradication. This study highlights the importance of continued research and the need for integrated strategies to combat malaria.

Keywords
Malaria control; Vector management; Vaccine development; Insecticide resistance; Plasmodium lifecycle
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