Xiaojie  Zhang

Beijing Tiantan Biological Products Co., Ltd., Chaoyang, 100024, Beijing, China
Author    Correspondence author
Journal of Vaccine Research, 2024, Vol. 14, No. 3   
Received: 08 Apr., 2024    Accepted: 12 May, 2024    Published: 24 May, 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study comprehensively examines the development trajectory of mRNA vaccine technology, highlighting its historical evolution, fundamental mechanisms, technological advancements, and various applications. We trace key milestones in mRNA technology, including crucial innovations in mRNA stability, delivery systems, and large-scale manufacturing. The study discusses the successful application of mRNA vaccines in infectious diseases, particularly during the COVID-19 pandemic, and explores their prospects in cancer immunotherapy. Despite their transformative potential, mRNA vaccines still face challenges related to safety, efficacy, regulatory and ethical issues, and public acceptance. Future research should emphasize next-generation vaccines, integration with other technologies, and global health impacts. This study underscores the revolutionary impact of mRNA vaccines on modern medicine and public health.

mRNA vaccines; Vaccine development; Immune response; Cancer immunotherapy; COVID-19