Yong Zhang

Beijing Sino Biopharmaceutical Co., Ltd., Chaoyang, 100020, Beijing, China
Author    Correspondence author
Journal of Vaccine Research, 2024, Vol. 14, No. 5   
Received: 15 Jul., 2024    Accepted: 31 Aug., 2024    Published: 07 Sep., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The development of multi-pathogen vaccines offers a promising approach to improving global immunization efforts by providing protection against multiple infectious pathogens with a single formulation. This study comprehensively evaluates the safety and efficacy of multi-pathogen vaccines, examining their historical development, biological and immunological foundations, and key case studies. While multi-pathogen vaccines have significant advantages in simplifying immunization schedules, reducing healthcare costs, and increasing vaccine coverage, they also face unique challenges such as immune interference, production complexity, and regulatory hurdles. This study discusses strategies to enhance the safety and efficacy of these vaccines, including the use of advanced adjuvants, optimized dosing regimens, novel delivery systems, and synergistic agents. The research provides valuable insights into the opportunities and challenges of multi-pathogen vaccines and emphasizes their potential role in addressing the global burden of infectious diseases. Keywords Multi-pathogen vaccines; Vaccine safety; Vaccine efficacy; Immune interference; mRNA technology

Multi-pathogen vaccines; Vaccine safety; Vaccine efficacy; Immune interference; mRNA technology