Jenny Wu

Institute of Life Science, Jiyang College of Zhejiang A&F University, Zhuji, 311800, China
Author    Correspondence author
International Journal of Molecular Medical Science, 2024, Vol. 14, No. 1   doi: 10.5376/ijmms.2024.14.0006
Received: 16 Feb., 2024    Accepted: 18 Mar., 2024    Published: 29 Mar., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Wu J., 2024, Application and prospects of gene editing technology in the treatment of neurological disorders, International Journal of Molecular Medical Science, 14(1): 42-47 (doi: 10.5376/ijmms.2024.14.0006)

Neurological diseases are a serious threat to human health, causing a huge burden on patients and society. Traditional treatment methods often cannot effectively cure neurological diseases, so it is necessary to explore new treatment strategies. The rapid development of gene editing technology has provided new ideas for the treatment of neurological diseases. This review will systematically review the application of gene editing technology in the treatment of neurological diseases. The review provides an overview of the principles and tools of gene editing technology, analyzes the characteristics of neurological diseases and the challenges of existing treatments, and explores in detail the application cases of gene editing technology in the treatment of neurological diseases such as neurodegenerative diseases and congenital neurological diseases. In addition, this review also discusses the challenges and safety considerations faced by gene editing technology, and looks forward to the future prospects and development directions. Comprehensive analysis shows that gene editing technology has enormous advantages and potential in the treatment of neurological diseases, bringing new hope to people.

Gene editing; Neurological disorders; CRISPR-Cas9; Neurodegenerative diseases; Congenital neurological disorders