Research Finds "Achilles heel" for Aggressive Prostate Cancer
Published:03 May2018 Source:Medical Xpress
US San Francisco researchers have discovered a promising new line of attacking against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.
Experiments in mice and with human cell showed that blocking this stress response with an experimental drug—previously shown to enhance cognition and restore memory after brain damage in rodents—causes treatment-resistant cancer cells to self-destruct while leaving normal cells unaffected.