Their technique could both simplify and advance the art of gene editing, not only for human diseases but also for basic biology research and crop engineering. It does so by leveraging transfer RNA (tRNA), a small molecule critical to protein synthesis, as a promoter that drives the expression of multiple guide RNAs (gRNAs) on a single array, then released individually by cells to direct the state-of-art genome editors (base editor or prime editor) for edits at multiple human genomic sites.