Simple and Reliable Early Prediction of Diabetes
Published:19 Feb.2024    Source:Ruhr-University Bochum
Diabetes often remains undetected until it has already damaged organs or nerves. This is partly due to the fact that diagnosis at an early stage is time-consuming and difficult. An international team of researchers headed by Associate Professor Dr. Johannes Dietrich from the Department of Medicine I of Ruhr University Bochum at St. Josef Hospital in Bochum, Germany, has shown that a mathematical calculation based on just two values taken from a blood sample enables the reliable and inexpensive diagnosis of diabetes at an early stage.
Researchers have researched a new method for the early detection of diabetes. The method, called SPINA Carb, is based on mathematical modeling. All that is required is a blood sample, which is taken in the morning before the patient's had their breakfast. Two values measured in the sample are relevant: the insulin value and the glucose value.

In computer simulations, the research team proved that the new parameter confirms the theory of dynamical compensation, which predicts that Insulin resistance in people with metabolic syndrome is compensated for by the pancreatic beta cells increasing their activity. A subsequent study of three groups of volunteers from the USA, Germany and India supported this assumption.